Algorithms and software for stochastic simulation of biochemical reacting systems

TitleAlgorithms and software for stochastic simulation of biochemical reacting systems
Publication TypeJournal Article
Year of Publication2008
AuthorsLi, H., Y. Cao, L. R. Petzold, and D. T. Gillespie
JournalBIOTECHNOLOGY PROGRESS
Volume24
Issue1
Pagination56-61
Date PublishedJAN-FEB
Type of ArticleProceedings Paper
ISSN8756-7938
Abstract

{Traditional deterministic approaches for simulation of chemically reacting systems fail to capture the randomness inherent in such systems at scales common in intracellular biochemical processes. In this manuscript,. we briefly review the state of the art in discrete stochastic and multiscale algorithms for simulation of biochemical systems and we present the StochKit software toolkit.}

DOI10.1021/bp070255h